Cohort information

ITALY				WP5
Organization		University of Trieste (UNITS)
Name of cohort		TRIESTE
Referring partner		UNIVR
Cohort Information	Country(-ies), cities, regions or centers involved	Trieste, Italy
	Time of data collection	03/2020	Ongoing
	Enrolment	Inactive
	Study setting	Single center
Population	Age	Adults
	Type	Retrospective
	Total number of patients	7960
Data collection	Clinical data	True
	Serological data	True
	Genetic data	False
	Sample collection	True
	Sample collected	Whole blood	Yes
		PBMC	No
		Dry-spot blood	No
		Plasma	No
		Serum	No
		Stool	No
		NP swabs	Yes
		Other	Salivary swabs
Description	The cohort consists of over seven thousand healthcare workers from ASUGI (Trieste, Gorizia), stratified by gender, age and job title. The subjects are vaccinated against SARS-CoV-2 and periodically tested with nasopharyngeal or salivary swabs. Subjects were also tested with serology test between after vaccination. Clinical data were collected via online questionnaire.
Publications	- Determinants of Anti-S Immune Response at 6 Months after COVID-19 Vaccination in a Multicentric European Cohort of Healthcare Workers – ORCHESTRA project [Frontiers in Immunology] - Determinants of Anti-S Immune Response at 9 Months after COVID-19 Vaccination in a Multicentric European Cohort of Healthcare Workers-ORCHESTRA Project [Viruses] - Primary SARS-CoV-2 Infections, Re-infections and Vaccine Effectiveness during the Omicron Transmission Period in Healthcare Workers of Trieste and Gorizia (Northeast Italy), 1 December 2021–31 May 2022 [Viruses] - Temporal trends of COVID-19 antibodies in vaccinated healthcare workers undergoing repeated serological sampling: An individual-level analysis within 13 months in the ORCHESTRA cohort [Frontiers in Immunology] - SARS-CoV-2 Reinfections in Health-Care Workers, 1 March 2020–31 January 2023 [Viruses]