Cohort information

ROMANIA				WP5
Organization		INSP
Name of cohort		INSP HCW
Referring partner		INSP
Cohort Information	Country(-ies), cities, regions or centers involved	Bucharest (and Southern regions), Iasi (and North-Eastern regions), Cluj, Timisoara (and Western regions)
	Time of data collection	05/2021	06/2021
	Enrolment	Inactive
	Study setting	Multi-centers
Population	Age	nan
	Type	Prospective
	Total number of patients	2698
Data collection	Clinical data	True
	Serological data	True
	Genetic data	False
	Sample collection	False
	Sample collected	Whole blood	NA
		PBMC	NA
		Dry-spot blood	NA
		Plasma	NA
		Serum	NA
		Stool	NA
		NP swabs	NA
		Other	NA
Description	Prospective cohort with online collection of data from HCWs working in various units: national/regional public health authorities, medical research institutes, hospitals, public/private medical practices, others. Baseline- collection of self-reported personal and clinical data (comorbidities, COVID19), job description, occupational risk and PPE, vaccination, risk perception, psychological effects of COVID19 pandemic. Follow-up on long term effects of COVID19, breakthrough infections, risk perception. Data on immune response (anti S quantitative testing) at 6M, 9M and 12M after full vaccination in a subsample of participants.
Publications	- ORCHESTRA project in Romania - a prospective occupational cohort to study the impact of COVID-19 pandemic on health care workers [Romanian Journal of Occupational Medicine] - Exhaustion in Healthcare Workers after the First Three Waves of the COVID-19 Pandemic [International Journal of Environmental Research and Public Health] - Determinants of Anti-S Immune Response at 6 Months after COVID-19 Vaccination in a Multicentric European Cohort of Healthcare Workers – ORCHESTRA project [Frontiers in Immunology] - Temporal trends of COVID-19 antibodies in vaccinated healthcare workers undergoing repeated serological sampling: An individual-level analysis within 13 months in the ORCHESTRA cohort [Frontiers in Immunology]