Cohort information

FRANCE				WP3
Organization		INSERM
Name of cohort		EPICOV
Referring partner		INSERM
Cohort Information	Country(-ies), cities, regions or centers involved	France
	Time of data collection	05/2020	03/2023
	Enrolment	Inactive
	Study setting	Multi-centers
Population	Age	Adolescents,Adults,Elderly
	Type	Retrospective
	Total number of patients	107759
Data collection	Clinical data	True
	Serological data	True
	Genetic data	False
	Sample collection	True
	Sample collected	Whole blood	No
		PBMC	No
		Dry-spot blood	Yes
		Plasma	No
		Serum	No
		Stool	No
		NP swabs	No
		Other	None
Description	The EpiCov study is a French, prospective, random population-based, socio-epidemiological cohort set up in April 2020. Individuals aged 15 years or older living in France (excluding people living in residences for elderly and living in jail) were randomly selected from the national Fichiers démographiques sur les logements et les individus (FIDELI) administrative sampling frame. Among the 134 391 people who responded the first round in May-June 2020, 107 759 responded to the second round in October-December 2020, and among them 85 074 responded to the third round in June-August 2021. Data were collected through computer-assisted-web interviews (CAWI) or computer-assisted-telephone interviews (CATI). Home self-sampling on dried blood were collected for central Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) Immunoglobulin G (IgG) antibodies testing during the first and second rounds. Home samples on DBS for detection IgG and neutralizing antibodies were collected in a random sub-sample of 12114 for 1st round of the EPICOV survey (May) and all respondents in November 2020. Purpose: provide national and regional estimate of sero-prevalence of SARS-CoV-2 infection and to analyze relations between living conditions and the dynamics of the epidemic. Additional questions: possible to add questions depending on respective agenda of EPICOV and ORCHESTRA. NB: multi-center is not adequate for our study. Consider it non applicable.
Publications	- Higher risk, higher protection: COVID-19 risk among immigrants in France-results from the population-based EpiCov survey [European Journal of Public Health] - Trends in social exposure to SARS-Cov-2 in France. Evidence from the national socio-epidemiological cohort – EPICOV [PLoS ONE] - Social Isolation Among Older Adults in the Time of COVID-19: A Gender Perspective [Frontiers in Public Health] - When Lack of Trust in the Government and in Scientists Reinforces Social Inequalities in Vaccination Against COVID-19 [Frontiers in Public Health] - Labor market participation and depression during the COVID-19 pandemic among young adults (18 to 30 years): A nationally representative study in France [Frontiers in Public Health] - Retrospective analysis of SARS-CoV-2 omicron invasion over delta in French regions in 2021-22: a status-based multi-variant model [BMC Infectious Diseases] - Use of health care services among people with COVID-19 symptoms in the first pandemic peak in France [PLoS ONE] - Comparison of Depression and Anxiety Following Self-reported COVID-19–Like Symptoms vs SARS-CoV-2 Seropositivity in France [JAMA Network Open] - Risk Factors for Community and Intrahousehold Transmission of SARS-CoV-2: Modeling in a Nationwide French Population-Based Cohort Study, the EpiCoV Study [American Journal of Epidemiology] - From intentions to practices: what drove people to get the COVID-19 vaccine? Findings from the French longitudinal socioepidemiological cohort survey [BMJ Open]