Cohort information

NETHERLANDS WP2
Organization UMCG
Name of cohort COVID-HOME
Referring partner UMCG
Cohort Information Country(-ies), cities, regions or centers involved UMCG Groningen
Time of data collection 03/2020 12/2022
Enrolment Inactive
Study setting Single center
Population Age Children,Adolescents,Adults,Elderly
Type Prospective
Total number of patients 182
Site of enrolment (WP2) Outpatient
Data collection Clinical data True
Serological data True
Genetic data True
Sample collection True
Sample collected Whole blood Yes
PBMC No
Dry-spot blood No
Plasma No
Serum No
Stool Yes
NP swabs Yes
Other None
Description The COVID-HOME study addresses key questions of relevance to guide patient care and inform public health guidelines for infection prevention and control in the community and household situation in a single study. The main strength of this study is the early, systematic and prospective follow-up of non-hospitalized SARS-CoV-2 patients during the acute disease evolution with a medium to long-term follow-up. The parameters collected in this study, such as viral load, antibody response, cytokine changes and clinical and laboratory parameters of patient evolution will allow the identification of independent factors/parameters determining evolution of disease, insight in other transmission routes than respiratory ones (such as sexual and faecal-oral), and immune response dynamics in non-hospitalized patients.